Dr Hiroki R. Ueda

Project Leader, Laboratory for Systems Biology
Manager, Functional Genomics Unit
RIKEN Center for Developmental Biology, Riken, Kobe


Email: uedah-tky@umin.ac.jp
Webpage link: http://www.cdb.riken.jp/lsb/index.html

Dr. Hiroki R. Ueda was born in Fukuoka, Japan, in 1975. He graduated from the Faculty of Medicine, the University of Tokyo, in 2000, and obtained his Ph.D in 2004 from the same university. While an undergraduate student, he worked as a research assistant on a biological simulation system project at Sony Computer Science Laboratories. While a graduate student, he next went on to work as a researcher from 2000 and then group leader from 2002 at Yamanouchi Pharmaceutical Co.

He was appointed as a team leader of laboratory for systems biology at RIKEN Center for Developmental Biology (CDB) from April, 2003 and promoted to be a project leader at CDB from September, 2009. He was also appointed as a manager of Functional Genomics Unit at the CDB from October, 2004. He also became a visiting professor in Tohoku University in April, 2005-March, 2006, Tokushima University from April, 2005 and National Institute of Genetics from April, 2010, and an invited professor of biology in Osaka University from April, 2006, and an invited professor of mathematics in Kyoto University from April, 2009.

He identified system-level network structure of mammalian circadian clocks. For this discovery, He received Tokyo Techno Forum 21, Gold Medal (Tokyo Techno Forum 21, 2005), Young Investigator Awards (MEXT, 2006) and IBM Science Award (IBM, 2009).  He recently solved the fundamental problem in chronobiology on the underling mechanism of singularity behavior of circadian clock that had been unsolved for more than 30 years. For this discovery, he received a Young Investigator Promotion Awards (Japanese Society for Chronobiology, 2007). He also recently discovered temperature-insensitive reaction in mammalian circadian clock, which will lead to a long-standing problem, "temperature-compensation" of circadian clock.   He invented diagnostic method of body time and rhythm disorders, which opens up the new possibility of chronotherapy. For this invention, he received Japan Innovator Awards (Nikkei Business Publications Inc. 2004).  His current research interests include system-level understanding of biological time, space and information, and systems-based medicine on human disease.  His current research interests include system-level understanding of biological time, space and information, and systems-based medicine on human disease.