 Dr Wei Chia-Lin
Senior Group Leader, Genome Technology & Biology
Group Leader, Clone Production & Management Genome Institute of Singapore
Email: weicl@gis.a-star.edu.sg
AREA OF RESEARCH
The primary focus of my research is to develop and apply sequencing based genomic technologies for genome and epigenome function elements interrogation pertinent to lineage specification and development. Using various second generation sequencing platforms, my research focuses on integrating the technology development effort to construct global, high resolution and unbiased functional networks constituted by the key genetic modulators in stem cell genomes and their dynamics throughput developmental process. Furthermore, we are also interest to characterize how these modulators can directly impact on gene expressions. Such knowledge will provide fundamental understanding in various nuclear processes including transcription, add new insight on the unique gene expression patterns crucial for cell fate determination and open the possibility of manipulating such structures to achieve cell type specific differentiation.
EDUCATION
1989-1994 Ph.D. Microbiology, University of California at Davis.
Dissertation: Cloning and characterization of eukaryotic translational initiation factor eIF-1A: Analysis of its role in protein synthesis.
Advisor: Dr. John W. B. Hershey
1984-1994 B.S. Medical Technology, National Yang-Ming University, Taiwan, R.O.C.
PROFESSIONAL APPOINTMENTS:
2009 Affiliated faculty position, Department of Biological Sciences
NationalUniversity of Singapore
2003 Senior Group Leader, Genome Technology and Biology
Genome Institute of Singapore
2002 – 2003 Group Leader, Cloning and Sequencing
Genome Institute of Singapore
2002 Group Leader,Molecular Biology
Odyssey Pharmaceuticals
1998 – 2002 Group Leader, Senior ScientistGenomics, Large Scale Biology Corp.
1994 – 1997 Postdoctoral Fellow, Department of Biology
Massachusetts Institute of Technology
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